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Bactrim Medication - Uses & Side Effects

Generic Name: Trimethoprim, Sulfamethoxazole

SULFAMETHOXAZOLE; TRIMETHOPRIM or SMX-TMP (Septra®, Bactrim™ DS, Co-Trimoxazole, and others) is a combination of two antibiotics. Sulfamethoxazole and trimethoprim are both antibiotics that treat different types of bacterial infections. Sulfamethoxazole and trimethoprim fight bacteria in your body. This drug is also used for traveler's diarrhea, and Pneumocystis carinii pneumonia in AIDS or cancer patients.

Bactrim Dosage

  • The usual adult dosage in the treatment of urinary tract infection is 1 Bactrim DS or 2 Bactrim tablets, or 4 teaspoonfuls (20 milliliters) of Bactrim Pediatric Suspension every 12 hours for 10 to 14 days.
  • For worsening of chronic bronchitis, the usual recommended dosage is 1 Bactrim DS, 2 Bactrim tablets, every 12 hours for 14 days.
  • For the teatment of Pneumocystis Carinii Pneumonia, the recommended dosage is 15 to 20 milligrams of trimethoprim and 75 to 100 milligrams of sulfamethoxazole per 2.2 pounds of body weight per 24 hours divided into equal doses every 6 hours for 14 to 21 days.

Uses of Bactrim

  • Bactrim is used to treat infections such as urinary tract infections, bronchitis, ear infections (otitis), traveler's diarrhea, and Pneumocystis carinii pneumonia.
  • It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type).

Side Effects of Bactrim

If you are taking this medication, then discuss the side effects with your doctor. If you feel any change in intensity, then you should tell your doctor. Because only your doctor can determine if it is safe to continue using Bactrim. Side effects may include:

  • Hives
  • lack or loss of appetite
  • nausea
  • skin rash
  • vomiting
  • Abdominal pain
  • allergic reactions
  • anemia
  • chills
  • convulsions
  • depression
  • diarrhea
  • eye irritation
  • fatigue
  • fever
  • hallucinations
  • headache
  • hepatitis
  • inability to fall or stay asleep
  • inability to urinate
  • increased urination

Warnings and precautions before taking Bactrim:

  • If you develop severe diarrhea, then you should call your doctor. Because this drug can cause a serious intestinal inflammation.
  • You should tell your doctor and pharmacist if you are allergic to cotrimoxazole, diuretics ('water pills', oral diabetes medications, any sulfa drug, or any other drugs.
  • You should tell your doctor and pharmacist if you are taking prescription and nonprescription medications, especially methotrexate, phenytoin, warfarin, and vitamins.
  • If you have or have ever had liver or kidney disease, asthma, severe allergies, or glucose-6-phosphate dehydrogenase (G-6-PD) deficiency (an inherited blood disease), then tell your doctor.

Drug Interaction :-

If you are taking certain drugs with Bactrim, then it may decreased, increased or altered the effects of Bactrim medicine. It is especially important to check with your doctor before combining Bactrim with the following:

  • mantadine (Symmetrel)
  • Blood thinners such as Coumadin
  • Cyclosporine (Neoral, Sandimmune)
  • Digoxin (Lanoxin)
  • Indomethacin (Indocin)
  • Methotrexate (Rheumatrex)
  • Oral diabetes medications such as Micronase and Glucotrol
  • Pyrimethamine (Daraprim)
  • Seizure medications such as Dilantin
  • Tricyclic antidepressants such as Elavil, Norpramin, Sinequan, and
  • Tofranil
  • Water pills (diuretics) such as HydroDIURIL
Overdose

When you are taking Bactrim, and you feel that overdose is suspected then contact your doctor immediately. Symptoms of an Bactrim overdose may include:-

  • nausea
  • vomiting
  • decreased appetite
  • diarrhea
  • headache
  • yellowing of the skin or eyes
  • decreased urine production
  • bloody urine
  • coma

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